mgb modulation Search Results


mgb modulation  (ATCC)
98
ATCC mgb modulation
Mgb Modulation, supplied by ATCC, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mgb modulation/product/ATCC
Average 98 stars, based on 1 article reviews
mgb modulation - by Bioz Stars, 2026-05
98/100 stars
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gene exp crem rn00569145 m1  (Thermo Fisher)
87
Thermo Fisher gene exp crem rn00569145 m1
RX1 and RX2 reduce levels of phospho-STAT3 but only RX2 blocks <t>ICER</t> induction . a Representative Western Blot analysis of whole-cell protein extracts from primary neurons 9 DIV pretreated with100nM Ruxolitinib (RX1), 10uM Ruxo (RX2), or DMSO for 1 h before the addition of BDNF. Cells were collected 30 min after BDNF administration and probed with anti pSTAT3, STAT3 and β-Actin. b Quantitation of signals from densitometry is displayed as mean percent change (±SEM) relative to the DMSO+Water control group (**p < 0.01). Ruxolitinib significantly reduces the levels of P-STAT3 with no change in total STAT3. c Graphical representation of results from real-time PCR analysis using specific Taqman probe and primers. RNA was extracted from cells collected 4 h after BDNF administration. Transcript levels are shown as the mean values (±SEM) of the ratio relative to the DMSO+Water control group for Icer n = 6. Note, that while RX1 blocks pSTAT3, it does not block the effect of BDNF treatment on ICER induction, while WP and RX2 do
Gene Exp Crem Rn00569145 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 87/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/gene exp crem rn00569145 m1/product/Thermo Fisher
Average 87 stars, based on 1 article reviews
gene exp crem rn00569145 m1 - by Bioz Stars, 2026-05
87/100 stars
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Image Search Results


RX1 and RX2 reduce levels of phospho-STAT3 but only RX2 blocks ICER induction . a Representative Western Blot analysis of whole-cell protein extracts from primary neurons 9 DIV pretreated with100nM Ruxolitinib (RX1), 10uM Ruxo (RX2), or DMSO for 1 h before the addition of BDNF. Cells were collected 30 min after BDNF administration and probed with anti pSTAT3, STAT3 and β-Actin. b Quantitation of signals from densitometry is displayed as mean percent change (±SEM) relative to the DMSO+Water control group (**p < 0.01). Ruxolitinib significantly reduces the levels of P-STAT3 with no change in total STAT3. c Graphical representation of results from real-time PCR analysis using specific Taqman probe and primers. RNA was extracted from cells collected 4 h after BDNF administration. Transcript levels are shown as the mean values (±SEM) of the ratio relative to the DMSO+Water control group for Icer n = 6. Note, that while RX1 blocks pSTAT3, it does not block the effect of BDNF treatment on ICER induction, while WP and RX2 do

Journal: BMC Genomics

Article Title: Evidence for a non-canonical JAK/STAT signaling pathway in the synthesis of the brain’s major ion channels and neurotransmitter receptors

doi: 10.1186/s12864-019-6033-2

Figure Lengend Snippet: RX1 and RX2 reduce levels of phospho-STAT3 but only RX2 blocks ICER induction . a Representative Western Blot analysis of whole-cell protein extracts from primary neurons 9 DIV pretreated with100nM Ruxolitinib (RX1), 10uM Ruxo (RX2), or DMSO for 1 h before the addition of BDNF. Cells were collected 30 min after BDNF administration and probed with anti pSTAT3, STAT3 and β-Actin. b Quantitation of signals from densitometry is displayed as mean percent change (±SEM) relative to the DMSO+Water control group (**p < 0.01). Ruxolitinib significantly reduces the levels of P-STAT3 with no change in total STAT3. c Graphical representation of results from real-time PCR analysis using specific Taqman probe and primers. RNA was extracted from cells collected 4 h after BDNF administration. Transcript levels are shown as the mean values (±SEM) of the ratio relative to the DMSO+Water control group for Icer n = 6. Note, that while RX1 blocks pSTAT3, it does not block the effect of BDNF treatment on ICER induction, while WP and RX2 do

Article Snippet: Assay ID: Ppia (housekeeping): Rn00690933_m1 VIC-MGB; Galr1: Rn04932425_m1 FAM-MGB; Drd5: Rn00562768_s1 FAM-MGB; Jak2: Rn00676341_m1 FAM-MGB; Gabrg2: Rn01464079_m1 FAM-MGB; Grm1: Rn00566625_m1 FAM-MGB; Icer: Rn00569145_m1 FAM-MGB; Ccnd1: Rn00432359_m1 FAM-MGB; Socs3: Rn00585674_s1 FAM-MGB; Mcl1: Rn00821024_g1 FAM-MGB; Cxcr4: Rn00573522_s1.

Techniques: Western Blot, Quantitation Assay, Control, Real-time Polymerase Chain Reaction, Blocking Assay